It’s in the same vein as gamma ray bursts. Could possibly cause problems, but space is so big, so heavily occupied by empty space, that the odds of ever encountering one vs just more empty space is almost infinity:1.

I mean, our planet is billions of years old and hasn’t encountered a single one yet, based on the fact it’s still comfortably in orbit around the sun.

Asteroids are far, far more concerning. Encountered a bunch of those already.